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子宫内膜异位症(EM)常引起疼痛和不孕。对于相关疼痛,各药物不良反应明显不同,但药物间疗效无明显差异。手术治疗可明显降低疼痛评分,但保守手术易复发。手术联合药物治疗的疗效不确定,尚需进一步研究。对于相关不孕的治疗,研究证实抑制卵巢功能的药物不利于生育改善,不推荐应用。手术对各期EM均有效,控制性超促排卵-人工授精适用于早期EM及手术治疗后的EM。手术联合促性腺激素释放激素激动剂作为重度EM的一线治疗方案,体外受精作为二线治疗方案。尚需对该病的发病机制进行研究,以从根本上治疗该病。
Endometriosis (EM) often causes pain and infertility. For related pains, the adverse reactions of each drug were significantly different, but no significant difference between the efficacy of the drug. Surgical treatment can significantly reduce the pain score, but conservative surgery is easy to relapse. The curative effect of surgery combined with drug therapy is uncertain and needs further study. For the treatment of infertility, the study confirmed that drugs that inhibit ovarian function is not conducive to the improvement of fertility, not recommended. Surgery is effective on all stages of EM, and controlled ovarian hyperstimulation - artificial insemination is suitable for early EM and EM after surgery. Surgery combined with gonadotropin-releasing hormone agonist as a first-line treatment of severe EM, IVF as a second-line treatment. Still need to study the pathogenesis of the disease in order to fundamentally treat the disease.