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目的观察中西医结合治疗儿童过敏性紫癜(Henoch-Schnlein purpura,HSP)反复发作及预防紫癜性肾炎(Henoch-Schnlein purpura nephritis,HSPN)发生的临床疗效。方法96例过敏性紫癜患儿随机分成治疗组(中西医结合治疗)和对照组,观察治疗后临床症状改善的情况,并观察治疗1个月、3个月、半年后HSP复发、HSPN发生的情况及血清免疫球蛋白IgA、血清补体C3的变化情况。结果治疗组经治疗1个月、3个月、半年后过敏性紫癜复发、紫癜性肾炎发生的情况均少于对照组(P<0.01),血清IgA、补体C3水平于治疗1个月后趋于正常,改善情况优于对照组(P<0.05)。结论中西医结合治疗可以减少过敏性紫癜复发及紫癜性肾炎的发生。
Objective To observe the clinical curative effect of Integrative Chinese and Western medicine on recurrent Henoch-Schnlein purpura (HSP) and prevention of Henoch-Schnlein purpura nephritis (HSPN) in children. Methods 96 cases of children with Henoch-Schonlein purpura were randomly divided into treatment group (Integrative Medicine) and control group, to observe the clinical symptoms after treatment, and to observe the treatment of 1 month, 3 months, six months after the HSP relapse, HSPN occurred Situation and serum immunoglobulin IgA, serum complement C3 changes. Results The treatment group experienced one month, three months and six months after the recurrence of anaphylactoid purpura, purpura nephritis were less than the control group (P <0.01), serum IgA, complement C3 levels in the treatment of 1 month after the trend In normal, improvement is better than the control group (P <0.05). Conclusion Integrative Medicine can reduce the recurrence of Henoch-Schonlein purpura and purpura nephritis.