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患者女性,29岁,主诉血小板减少。初期出现雷诺氏现象,诊断为雷诺氏病,开始用PSL40mg/d。此后出现多发性关节疼痛,疑为SLE。以PSL12mg/d的维持量治疗,但出现血小板减少(6.3×10~9/L),PSL增至20mg/d。1987年4月PSL减至18mg/d,其后,抗DNA抗体逐渐增加,呈进行性低补体血症及血小板减少。患者拒绝增加PSL用量及住院治疗。1988年3月于门诊加用柴苓汤(9g/d)治疗。
Female patient, 29 years old, complains of thrombocytopenia. Raynaud’s phenomenon appears early, the diagnosis of Raynaud’s disease, began to use PSL40mg / d. Since then there are multiple joint pain, suspected SLE. Treatment with PSL 12 mg / d maintenance, but with thrombocytopenia (6.3 × 10 ~ 9 / L), PSL increased to 20mg / d. April PSL reduced to 18mg / d, thereafter, anti-DNA antibodies gradually increased, progressive hypocomplementemia and thrombocytopenia. Patients refused to increase the amount of PSL and hospitalization. March 1988 in the clinic plus Chailing soup (9g / d) treatment.