乳酸酸中毒(Lactic acidosis)是因体内乳酸盐和H~+的积蓄而引起的代谢性酸中毒。由于发病迅速,病死率高,因而受到临床上的普遍关注。鉴于该病的诊断和治疗有其独特之处,有必要作一全面介绍,本文仅就小儿乳酸酸中毒的原因、诊断及治疗等问题概述如下。乳酸的代谢及其特点乳酸是糖代谢无氧酵解的终末产物,其前质为丙酮酸,丙酮酸在体内与乳酸的相互转变如下图所示: Lactic acidosis is metabolic acidosis caused by the accumulation of lactate and H ~ + in the body. Due to rapid onset, high mortality, which has been the general concern in the clinic. In view of the disease diagnosis and treatment of its unique, it is necessary to make a comprehensive introduction, this article only on the causes of lactic acidosis, diagnosis and treatment of other issues are summarized below. Lactic acid metabolism and its characteristics Lactic acid is the end product of glucose metabolism anaerobic glycolysis, the precursor of pyruvate, pyruvate in vivo and lactate mutual transformation as shown below: