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作者采用清醒家兔静脉滴注给药方法研究了氨苯蝶啶对强心甙毒性的拮抗作用。试验用体重1.7~2.2kg的家兔,先按5或10mg/kg给予氨苯蝶啶口服,然后静脉滴注哇巴因(毒毛旋花子甙G)的稀释液以测定其毒性作用。结果:对照组、低剂量和高剂量氨苯蝶啶组家兔,哇巴因的致心律失常剂量分别为
The authors used awake rabbit intravenous infusion method to study the triamterene on the cardiac glycosides antagonism. Test rabbits weighing 1.7-2.2 kg were given oral triamterene at 5 or 10 mg / kg and then intravenously diluted with ouabain (venom G) to determine their toxic effects. Results: In the control group, the induced arrhythmia doses of rabbits and ouabain in the low-dose and high-dose triamterene groups were