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目的:分析采用兰索拉唑联合莫沙必利治疗反流性食管炎的治疗效果。方法:选取在2010年5月～2011年5月期间我院收治的反流性食管炎98例,将其随机分为两组:观察组49例,对照组49例,其中观察组采用兰索拉唑联合莫沙必利治疗,对照组采用单纯的兰索拉唑治疗。观察两组患者的泛酸、烧心等症状及不良反应情况,并做详细记录。结果:在临床表现效果判定结果中,观察组的总有效率为93.9%,对照组的总有效率为77.6%;在胃镜检查效果判定结果中,观察组的总有效率为89.8%,对照组的总有效率为73.5%。观察组治疗效果明显优于对照组,且差异显著(P<0.05),具有统计学意义。两组患者均未出现明显不良反应。结论:采用兰索拉唑联合莫沙必利治疗反流性食管炎疗效理想,值得临床推广。
Objective: To analyze the therapeutic effect of lansoprazole combined with mosapride on reflux esophagitis. Methods: 98 cases of reflux esophagitis treated in our hospital from May 2010 to May 2011 were randomly divided into two groups: observation group (49 cases) and control group (49 cases), in which the observation group adopted Lansuo Lazole combined with mosapride treatment, the control group treated with simple lansoprazole. Two groups of patients were observed pantothenic acid, heartburn and other symptoms and adverse reactions, and make a detailed record. Results: In the results of clinical manifestations, the total effective rate was 93.9% in the observation group and 77.6% in the control group. The total effective rate in the observation group was 89.8% in the control group The total effective rate was 73.5%. The treatment group was significantly better than the control group, and the difference was significant (P <0.05), with statistical significance. No significant adverse reactions occurred in both groups. Conclusion: Lansoprazole combined with mosapride in the treatment of reflux esophagitis effective and worthy of clinical promotion.