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本文报道应用ABC(Avidin-Biotin-Peroxidase-Complex)方法与单克隆抗体标记67例恶性淋巴瘤。对照组标记了24例包括慢性淋巴结炎,何杰金病、转移性癌等。34例淋巴结内淋巴瘤中,16俐被证实为T细胞性淋巴瘤,占淋巴结内淋巴瘤的47.1％。16例T细胞性淋巴瘤中15例是属于辅助型T细胞的亚群(Leul~+、Leu4~+、Leu3a~+),16例的Ⅰ_a均阳性。其余18例被证实为B细胞性淋巴瘤,其中K阳性的有14例,λ阳性的有4例。10例皮肤淋巴瘤中肯定是CTCL的有8例,这8例的Ⅰ_a均阳性,8例中有1例M阳性,其他7例是属于辅助性T细胞的亚群。7倒中有2例较为罕见,他们的T_6阳性,有1例皮肤与淋巴结的肿瘤显示相同的标记结果。
This article reports the use of ABC (Avidin-Biotin-Peroxidase-Complex) method and monoclonal antibody-labeled 67 cases of malignant lymphoma. Control group marked 24 cases including chronic lymphadenitis, Hodgkin’s disease, metastatic cancer. Of the 34 cases of lymph node lymphoma, 16 Li was confirmed as T-cell lymphoma, accounting for 47.1% of lymph node lymphoma. Of the 16 T-cell lymphoma cases, 15 were subpopulations of helper T cells (Leul ~ +, Leu4 ~ +, Leu3a ~ +), and 16 of them were positive for Ⅰ-a. The remaining 18 cases were confirmed as B-cell lymphoma, of which 14 cases of K-positive, λ-positive in 4 cases. Of the 10 cases of cutaneous lymphoma, 8 were positive for CTCL. All 8 were positive for Ⅰ_a, 1 was positive for M in 8 and 7 were subpopulations of helper T cells. Two of the seven were found to be rare, their T_6 positive, and one case of skin and lymph node tumors showed the same labeling results.