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本文报告６７例运动神经元病（ＭＮＤ）患者肌活检组织的光镜及酶组织化学检查的结果，其中２２例作过电镜观察；并与其它易混淆病（成年型脊髓性肌萎缩症、青年单侧上肢远端肌萎缩症、颈椎病和某些较慢性的周围神经病）７０例作对比研究。结果表明ＭＮＤ的肌肉病理有其特点，认为肌活检可作为ＭＮＤ诊断和鉴别诊断的重要辅助检查手段。
In this paper, we report the results of light microscopy and enzyme histochemical examination of muscle biopsy in 67 patients with motor neuron disease (MND). Twenty-two of them were observed by electron microscopy and compared with other confounding diseases (adult spinal muscular atrophy, Unilateral upper extremity muscular atrophy, cervical spondylosis and some of the more chronic peripheral neuropathy) 70 cases for comparative study. The results showed that the muscle pathology of MND has its own characteristics, that muscle biopsy can be used as MND diagnosis and differential diagnosis of important auxiliary examination.