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干扰素的发现迄今已有21年,最近,Merigan等在双盲对照试验中,证实白细胞干扰素可减少癌症患者皮肤带状疱疹的播散。干扰素治疗组患者的内脏合并症和疱疹后神经痛都比安慰剂组少而轻。这些观察提出两个相关的问题:(1)为什么人体干扰素的疗效经过这么长时间才得到证实?(2)使用干拢素的展望如何?
The discovery of interferon has been around for 21 years and recently, Merigan et al. Demonstrated in double-blind, controlled trials that leukocyte interferon could reduce the spread of cutaneous shingles in cancer patients. Patients with interferon therapy had fewer and fewer visceral and postherpetic neuralgia than placebo. These observations raise two related questions: (1) Why has the efficacy of human interferons been confirmed for such a long time? (2) What is the prospect of using it?