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目的研究3种微量元素锰、铅、铝对正常人的心血管自主神经功能以及神经行为功能的影响,以及心血管自主神经功能对神经行为的影响。方法采用Ewing DJ推荐的心血管自主神经功能测试组合(ANS)测试正常人心血管自主神经系统功能,采用世界卫生组织(WHO)推荐的神经行为核心测验组合判断研究对象的情感状态和认知功能。使用石墨炉原子吸收分光光度法测定血锰浓度、血铅浓度和尿铝浓度。对三者进行Pearson相关分析。结果微量元素中血锰和血铅与心血管自主神经功能存在显著相关;尿铝与心血管自主神经功能相关性不显著;血锰、血铅、尿铝与神经行为功能的相关性体现在不同方面;心血管自主神经功能与神经行为功能的某些方面相关。结论微量元素锰、铅、铝可能影响心血管自主神经功能以及神经行为功能的不同方面。
Objective To study the effects of three trace elements, manganese, lead and aluminum on cardiovascular autonomic function and neurobehavioral function in normal subjects and the effects of cardiovascular autonomic function on neurobehavioral changes. Methods The function of cardiovascular autonomic nervous system (CNV) in normal subjects was tested by Ewing DJ’s recommended cardiovascular autonomic nervous system functional test combination (ANS), and the emotional state and cognitive function of the subjects were judged by the combination of the neurobehavioral core test recommended by the World Health Organization . Graphite furnace atomic absorption spectrophotometric determination of blood manganese concentration, blood lead concentration and urine aluminum concentration. Pearson correlation analysis of the three. Results There was a significant correlation between serum manganese and blood lead and cardiovascular autonomic function in trace elements. The correlation between urine aluminum and cardiovascular autonomic nervous function was insignificant. The correlation between blood manganese, blood lead, urine aluminum and neurobehavioral function was different Aspects; cardiovascular autonomic function is associated with certain aspects of neurobehavioral function. Conclusion The trace elements manganese, lead and aluminum may affect different aspects of cardiovascular autonomic function and neurobehavioral function.