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目的探讨阿奇霉素序贯治疗支原体肺炎患儿的临床效果。方法选取2013年1月至2014年11月邳州市人民医院收治的支原体肺炎患儿84例为研究对象,按随机数字表法将其分为对照组和观察组,各42例。对照组患儿采用阿奇霉素静脉注射治疗8 d,观察组患儿静脉注射阿奇霉素3 d后使用口服给药方式,比较两组患儿的临床疗效及并发症发生情况。结果观察组患儿的总有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患儿呕心呕吐、腹痛、静脉滴注痛的发生率均明显低于对照组,差异均有统计学意义(均P<0.05);两组患儿的皮疹发生率差异无统计学意义(P>0.05)。结论阿奇霉素序贯治疗小儿支原体肺炎的临床效果明显,可降低相关并发症的发生。
Objective To investigate the clinical effect of azithromycin sequential therapy in children with mycoplasma pneumonia. Methods 84 children with mycoplasmal pneumonia admitted in Danzhou People’s Hospital from January 2013 to November 2014 were selected as the research objects, and divided into control group and observation group according to the random number table method, with 42 cases in each group. Children in the control group were treated with intravenous azithromycin for 8 days. The patients in the observation group received oral administration of azithromycin 3 days after intravenous injection. The clinical efficacy and complications of the two groups were compared. Results The total effective rate in the observation group was significantly higher than that in the control group (P <0.05). The incidences of vomiting, abdominal pain and intravenous drip pain in the observation group were significantly lower than those in the control group (P <0.05). There was no significant difference in the incidence of rash between the two groups (P> 0.05). Conclusion Sequential azithromycin treatment of children with mycoplasma pneumonia clinical effect is obvious, can reduce the incidence of complications.