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中性粒细胞(PMN)活化对血管的损伤作用与多种疾病的发展与转归有关。但有关PMN致血管损伤的具体环节还不清楚。我们观察了活化PMN产生弹性蛋白酶(NE)及超氧化物的情况及活化PMN与肺血管损伤的关系,结果表明:FMLP和A23187刺激的PMN释放NE分别从9.39±1.49%升至15.67±0.15(p<0.05)和
Neutrophil (PMN) activation of vascular damage and a variety of diseases related to the development and outcome. However, the specific links of vascular damage caused by PMN is not yet clear. We observed the relationship between activated PMN production of elastase (NE) and superoxide and activation of PMN and pulmonary vascular injury. The results showed that the NE release of PMN stimulated by FMLP and A23187 increased from 9.39 ± 1.49% to 15.67 ± 0.15 ( p <0.05) and