先天性无虹膜是一种较少见的先天畸形，发生率有报道约1／10万。作者遇到一家系三代12人中有4人患病，报道如下。1临床资料例1：女，8岁。因左眼被石块击伤1d就诊。查视力：右0．4，在外人左眼上睑皮下瘀血肿胀，结膜无充血，角膜透明，KP（－），房闪（＋），无虹膜，可见晶状 Congenital absence of iris is a less common form of congenital malformations, the incidence has been reported about 1/10 million. The author encountered a family of 12 people in three generations of illness, reported as follows. 1 clinical data example 1: female, 8 years old. Because the left eye was injured 1d stone treatment. Check visual acuity: right 0.4, in the left eye eyelid outside the blood stasis swelling, conjunctival hyperemia, corneal transparency, KP (-), atrial flash (+), no iris, visible crystalline