金龙胆草系菊科白酒草属植物苦蒿(conyzablinii Le’vl),临床用于治疗慢性气管炎有一定疗效,无明显副作用。金龙胆草含皂甙、树脂、酸性物质、酚类、鞣质、还原糖及微量挥发油成分。我们从中提取分离出有效成分总皂甙(5个化合物的混合物),用硫酸水解后,经硅胶柱层析和氯仿甲醇洗脱,分离得到具有生理活性的甙元A和B,甙元A元素分析:实验数C73.54%、H10.05%;计算值C73.74%、H9.90%;紫外光谱最大吸收为212nm处,可能无共轭体系,红外光谱(cm~(-1))显示有羟基和羰基,并具有三萜基本骨架的特征吸收,质谱图显示分子离子峰的质荷比为488,分子式应为C_(30)H_(48)O_5,与元素分析值吻合,其结构的研究工作正在进行中。本 Golden gentian is a family of Conyzablinii Le’vl. It is clinically used for the treatment of chronic bronchitis with certain efficacy and no obvious side effects. Gold gentian contains saponins, resins, acids, phenols, tannins, reducing sugars, and trace volatile oils. We extracted and separated the active ingredient total saponins (a mixture of 5 compounds) and hydrolyzed with sulfuric acid. After silica gel column chromatography and chloroform methanol elution, isolated physiologically active aglycones A and B were isolated. : Number of experiments C73.54%, H10.05%; Calculated value C73.74%, H9.90%; UV absorption maximum 212nm, may not have conjugated system, infrared spectrum (cm~(-1)) display It has hydroxyl and carbonyl groups, and has a characteristic absorption of the triterpene skeleton. The mass spectrum shows that the mass-to-charge ratio of the molecular ion peak is 488, and the molecular formula is C_(30)H_(48)O_5, which is consistent with the elemental analysis values. Research work is ongoing. this