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目的分析美托洛尔联合胺碘酮在冠心病心律不齐患者治疗中应用的临床效果。方法选取2015年1月-2017年2月广州医科大学附属第六医院清远市人民医院收治的52例冠心病心律不齐患者为研究对象,按随机数字表法分为观察组和对照组各26例,观察组予以美托洛尔联合胺碘酮治疗,对照组予以胺碘酮治疗,比较两组治疗效果。结果两组治疗后室性早搏数、房性早搏数、交界性早搏数、心率和QT间期离散度(QTd)比较,差异有统计学意义(P<0.05),治疗后均显著下降,且治疗后观察组的TC、TG、LDL-C水平低于对照组,差异有统计学意义(P<0.05)。观察组显效率和总有效率高于对照组,差异有统计学意义(P<0.05)。结论美托洛尔与胺碘酮联合治疗冠心病心律不齐效果较好,值得推广。
Objective To analyze the clinical effect of metoprolol combined with amiodarone in the treatment of patients with coronary heart disease and arrhythmia. Methods Fifty-two patients with arrhythmia of coronary heart disease admitted from Qingyuan People’s Hospital, the sixth affiliated hospital of Guangzhou Medical University from January 2015 to February 2017 were divided into observation group and control group according to random number table Cases, the observation group metoprolol combined with amiodarone treatment, the control group was amiodarone treatment, the treatment effect was compared. Results There were significant differences in the number of ventricular premature beat, atrial premature beat, borderline premature beat, heart rate and QTd between the two groups after treatment (P <0.05) The levels of TC, TG and LDL-C in the observation group after treatment were lower than those in the control group, with significant difference (P <0.05). The observation group was significantly higher efficiency and total effective rate than the control group, the difference was statistically significant (P <0.05). Conclusion Metoprolol combined with amiodarone in the treatment of coronary heart disease arrhythmia better, it is worth promoting.