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本文通过对肝炎患儿、其他疾病患儿、HBsAg 携带者及无肝病正常小儿的 RIF 动态变化、其他免疫反应指标及 RIF 在体外对免疫反应的影响等观察,结果表明: 1.RIF变化与肝炎病情有密切关系。肝炎组 RIF阳性率显著高于其他组。RIF持续存在或抑制率升高,均提示疾病的迁延。动态检测 RIF 可作为判断肝炎病人临床转归的参考指标。 2.RIF对机体免疫功能的影响主要反映在抑制E_t花环形成。RIF可能通过对E受体功能的作用来影响机体的免疫功能。但未观察到RIF对E_a花环形成的影响。 3.RIF阳性血清在体外对 LMI、LAI 未见有明显的抑制作用。
In this paper, the dynamic changes of RIF, other immune response indexes and the impact of RIF on immune response in children with hepatitis, children with other diseases, HBsAg carriers and normal children without liver disease were observed. The results showed that: 1.RIF changes and hepatitis The condition is closely related. The positive rate of RIF in hepatitis group was significantly higher than that in other groups. The persistence of RIF or the increased inhibition rate suggest a delay in disease progression. Dynamic detection of RIF can be used as a reference to determine the clinical outcome of patients with hepatitis. 2.RIF immune function of the body mainly reflected in the inhibition of E_t rosette formation. RIF may affect the body’s immune function through its effect on E receptor function. However, no effect of RIF on the formation of E_a rosette was observed. 3. RIF positive serum in vitro LMI, LAI no significant inhibitory effect.