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目的:探讨中国人群中ABO血型与急性非ST段抬高型心肌梗死(NSTEMI)的相关性.方法:回顾性分析北京安贞医院2013-01至2014-12收治入院的1039例NSTEMI患者(病例组)和经冠状动脉(冠脉)造影证实冠脉正常的1039例患者(对照组)的ABO血型的临床资料.观察记录研究对象的临床资料,包括年龄、既往病史及ABO血型等.采用Logistic回归模型进行单因素及多因素分析.结果:在病例组和对照组中:A血型287例(27.6％)和259例(24.9％),B血型345例(33.3％)和356例(34.3％),AB血型102例(9.8％)和114例(11.0％),O血型305例(29.4％)和310例(29.8％),两组ABO血型分布差异无统计学意义.按A血型与非A血型、B血型与非B血型、AB血型与非AB血型和O血型与非O血型分析,在两组间分布差异均无统计学意义(P>0.05).经多因素Logistic回归分析,在调整年龄、性别、高血压病、糖尿病、高脂血症、脑血管疾病和吸烟等心肌梗死危险因素后,模型显示A、B及AB血型者罹患NSTEMI的风险与O血型者相似;A、B、AB及O血型与NSTEMI的发生均没有相关性.结论:ABO血型与NSTEMI的发生无关.“,”Objective: To explore the relationship between ABO blood group and acute non-ST-segment elevation myocardial infarction (NSTEMI) occurrence. Methods: Our research included 2 groups: NSTEMI group, 1039 relevant patients treated in Anzhen hospital from 2013-01 to 2014-12 were retrospectively enrolled; Control group, 1039 subjects with normal coronary artery which was confirmed by coronary angiography. The Baseline condition including age, previous disease history and ABO blood group was studied. Logistic regression model was used to conduct single and multivariate analysis. Results: In NSTEMI group and Control group, blood type A was 287/1039 (27.6％) vs 259 (24.9％), type B was 345 (33.3％) vs 356 (34.3％), type AB was 102 (9.8％) vs 114 (11.0％) and type O was 305 (29.4％) vs 310 (29.8％), ABO blood group distribution for A and non-A, B and non-B, AB and non-AB blood group, O and non-O had no statistic meaning between 2 groups, P>0.05. Logistic regression analysis indicated that with adjusted risk factors of MI such as age, gender, hypertension, diabetes, hyperlipemia, cerebrovascular disease and smoking, the patients with blood types A, B and AB had the similar risk for NSTEMI occurrence than type O patients; there was no relationship between ABO blood group and NSTEMI occurrence. Conclusion: ABO blood group had no relationship to NSTEMI occurrence.