一项最新研究表明,近30%的患者在出现不良反应后未处方他汀治疗,而继续处方应用他汀者的心血管事件及死亡风险可降低10%~20%。研究者美国布莱根妇女医院的Alexander Turchin等对2000~2011年28 266例应用他汀后出现至少一种不良反应的成人患者进行分析,其中8277例未继续进行他汀治疗。不良反应方面,肌痛及其他肌肉骨骼症状是最常见的不良反应,发生率分别为24.6%和17.8%。中位随访4.4年发现, A recent study showed that nearly 30% of patients undergoing unirradiated statin therapy after adverse events, while the risk of cardiovascular events and death from continued statin use can be reduced by 10% to 20%. Researchers at the Brigham and Women’s Hospital in England, Alexander Turchin and colleagues analyzed 28 266 adult patients who experienced at least one adverse reaction after statin use between 2000 and 2011, of whom 8,277 did not continue statin treatment. Adverse reactions, muscle pain and other musculoskeletal symptoms are the most common adverse reactions, the incidence was 24.6% and 17.8%. In the median follow-up of 4.4 years,