抗肿瘤血管治疗具有高效、抑瘤谱广、不易产生耐药和无明显毒副作用等优势。近年来抗肿瘤血管治疗的常用策略是干扰血管生成调节因子从而抑制血管生成;由于肿瘤血管内皮细胞与正常血管内皮细胞存在质的区别,具有免疫原性,抗肿瘤血管免疫治疗有望成为另一种新方法。现综述抗肿瘤血管治疗的优势、主要策略和存在的不足。 Anti-tumor vascular treatment with high efficiency, broad anti-tumor spectrum, not easy to produce resistance and no obvious side effects and other advantages. In recent years, anti-tumor vascular therapy commonly used strategy is to interfere with angiogenesis regulators and thus inhibit angiogenesis; due to tumor vascular endothelial cells and normal vascular endothelial cells there is a qualitative difference, with immunogenicity, anti-tumor vascular immune therapy is expected to become another new method. Now summarize the advantages of anti-tumor vascular therapy, the main strategies and shortcomings.