氧化乙烯已用来作为乙烯甘油生产中的中间产??物(抗冻产物)、杀真菌剂以及食品和医院装备的消毒剂。环绕世界有很多工人暴露在氧化乙烯中(如,在美国,1977年仅医疗及有关设备中被暴露的工人总数估计超过10万人)。氧化乙烯对人体毒性的文献,主要是与初发性刺激及皮肤过敏性有关。已观察到,受暴露的鼠骨髓细胞及意外伤害所暴露的人淋巴细胞染色体的过度畸变。该等早期的某些发现,导致注意氧化乙烯可能为人致癌原。本文报道,1972～1977年间瑞典一所小型技术工厂工人中发生了3例白血病。该厂于1968年起应用氧化乙烯及甲醛消毒医院器材。1977年,瑞典职业安全健康管理局(SOSHA)通报,认为这发生得似过于频繁。仅一些人用氧化乙烯进行消毒工作,而处理贮库箱合工作的30名妇女与消毒本身无 Ethylene oxide has been used as an intermediate product (antifreeze product) in the production of ethyleneglycerol, a fungicide and a disinfectant for food and hospital equipment. Many workers around the world are exposed to ethylene oxide (eg, in the United States, the total number of workers exposed to medical and related equipment in 1977 was estimated at more than 100,000). The toxicity of ethylene oxide to human literature, mainly associated with primary irritation and skin allergies. It has been observed that the chromosomal aberrations of the exposed lymphocytes of exposed mouse bone marrow cells and accidental injury are exposed. Some of these early findings led to noting that ethylene oxide may be a human carcinogen. This article reports three cases of leukemia in a small skilled factory worker in Sweden between 1972 and 1977. The plant in 1968 from the use of ethylene oxide and formaldehyde disinfection of hospital equipment. In 1977, the Swedish Occupational Safety and Health Administration (SOSHA) informed that this had occurred too often. Only some people use ethylene oxide to disinfect the work, while the 30 women who deal with the storage box work together with the disinfection itself