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目的探讨与分析罗库溴铵预处理对小儿肌松起效的影响。方法选择2009年10月～2010年10月在某院就诊的择期全麻手术患儿90例,随机均分为两组:对照组在麻醉诱导前预先静脉注射生理盐水0.5ml,观察组预先静脉注射罗库溴铵0.06mg/kg,比较两组起效时间及肌松时效。结果两组ThD75、ThD90、ThDmax时间经比较,差异均有统计学意义(P﹤0.05)。两组T125%恢复时间、T150%恢复时间、T175%恢复时间及恢复指数相比,差异均无统计学意义(P﹥0.05)。结论罗库溴铵预处理能缩短肌松起效时间,但对罗库溴铵肌松时效无明显影响。
Objective To investigate and analyze the effect of rocuronium pretreatment on the onset of muscle relaxant in children. Methods Ninety children undergoing elective general anesthesia in a hospital from October 2009 to October 2010 were randomly divided into two groups: the control group received intravenous injection of 0.5 ml normal saline before induction of anesthesia, Rocuronium 0.06mg / kg, the onset time and muscle relaxation of two groups were compared. Results The difference of ThD75, ThD90 and ThDmax time between the two groups was statistically significant (P <0.05). T125% recovery time, T150% recovery time, T175% recovery time and recovery index between the two groups, the difference was not statistically significant (P> 0.05). Conclusion The rocuronium preconditioning can shorten the onset time of muscle relaxant, but has no obvious effect on the relaxation effect of rocuronium.