海绵肾合并肾小管酸中毒是罕见病例,最近国内仅报告两例。我院亦曾收治一例,报告如下、男,23岁,工人,住院号49162。因肌无力反复发作3年余,多尿、烦渴、多饮1年余,于1982年9月1日拟诊“尿崩症”入院。患者于1979年7月间无明显诱因,夜睡中突然四肢无力,不能活动,4天后未经治疗症状消失。1979年11月及1980年初先后又发生两次。1980年7月后肌无力发作频繁,约一个月发作一次。多次外院诊为“周期性麻痹”,用过氯化钾、维生素B_(12)等治疗,无明显好转。1981年初,肌无力反复发作仍频繁,且渐出现多尿、多饮、烦渴。每天尿量多达5000ml,饮水量每日由2500ml增至1万ml。胃纳减退,体重减轻,大便干结,无尿频、尿急与尿痛。患者7～8岁曾患“急性肾炎”,据说已愈。半 Sponge and renal tubular acidosis is a rare case, the recent report of only two cases in China. Our hospital has also admitted a case, the report is as follows, male, 23 years old, worker, hospital number 49162. Repeated episodes of myastheniamia more than 3 years, more urine, polydipsia, drink more than 1 year, on September 1, 1982 proposed diagnosis of “diabetes insipidus” admission. Patients in July 1979 no obvious incentive to suddenly fell asleep at night, unable to move, no symptoms disappeared after 4 days. In November 1979 and early 1980, it happened twice in succession. Myasthenia gravis attack in July 1980 frequent, about once a month attack. Multiple out-patient clinics as “periodic paralysis”, with potassium chloride, vitamin B_ (12) and other treatment, no significant improvement. Early 1981, repeated episodes of muscle weakness is still frequent, and gradually appear polyuria, drink more, polydipsia. Daily urine output up to 5000ml, daily water intake from 2500ml to 10,000 ml. Loss of appetite, weight loss, dry stool, frequent urination, urgency and dysuria. Patients 7 to 8 years old had “acute nephritis”, is said to have been more. half