在体外受精—胚胎移植(IVF)治疗周期中,为了提高成功率,临床上普遍采用大剂量的促性腺素,通过控制性超排卵在一个周期获得多枚成熟卵母细胞。但是随着促性腺素的广泛应用,其副作用也逐渐显现:最为突出的是卵巢过度刺激综合征(OHSS),不仅损害胚胎的植入和发育,重度的OHSS甚至危及母亲生命。其发生率为1%~4%。为解决 In the IVF cycle, in order to increase the success rate, it is commonly accepted that large doses of gonadotropins are clinically used to obtain multiple mature oocytes at one cycle through controlled superovulation. However, with the wide application of gonadotropin, its side effects gradually appear: the most prominent is ovarian hyperstimulation syndrome (OHSS), which not only impairs embryo implantation and development, but also seriously endangers mother’s life. The incidence rate of 1% to 4%. To solve