多氯联苯化合物(PCBs)具有类雌激素样作用,可通过模拟和拮抗机体内源性雌激素作用,改变内源性激素的合成、代谢和激素受体水平,引起生殖发育异常、生殖功能障碍和神经发育障碍等[1]。本研究以舟山群岛作为研究现场开展流行病学研究,了解该地区育龄妇女体内多氯联苯的暴露水平,以及与新生儿出生缺陷之间的关系,现将 Polychlorinated biphenyls (PCBs) have estrogen-like effects that mimic and antagonize the body’s endogenous estrogen effects by altering the synthesis, metabolism, and hormone receptor levels of endogenous hormones, causing reproductive development dysfunction, reproductive dysfunction And neurodevelopmental disorders [1]. In this study, the epidemiological study of Zhoushan Islands as a research site to understand the level of exposure of PCBs in women of childbearing age in the region, as well as the relationship between birth defects and neonatal