论文部分内容阅读
1病例介绍患者1男,39岁。14岁时突发呼之不应,双眼向上凝视,继而出现四肢阵挛,持续数分钟后自行缓解。偶有舌咬伤,发作后感头晕不适,不伴大小便失禁。平均每周发作1次。在当地医院诊断为癫痫,治疗情况不详。为进一步诊治,患者于2012年8月来四川大学华西医院门诊就诊,头颅MRI检查未见明显异常,常规脑电图示广泛痫样放电。结合患者的病史特点及相关检查,诊断为癫痫全面性强直-阵挛发作。给予卡马西平治疗,0.1 g,3次/d,口服;2个月后患者癫痫发作次数得到一定控制,但每个月仍有2次左右发作。为了更好地控制癫痫发作,加用托吡酯,从50 mg/d,
1 case description Patient 1 male, 39 years old. Suddenly when the age of 14 should not call, his eyes staring upward, followed by limbs clonus, sustained self-ease after a few minutes. Occasional tongue bites, dizziness and discomfort after onset, not accompanied by incontinence. An average of 1 episode per week. Diagnosis of epilepsy in the local hospital, the treatment is unknown. For further diagnosis and treatment, patients in August 2012 to the West China Hospital of Sichuan University clinic, head MRI showed no significant abnormalities, conventional EEG showed extensive epileptiform discharge. Combined with the characteristics of the patient’s history and related tests, diagnosis of epilepsy with comprehensive tonic-clonic seizures. Give carbamazepine treatment, 0.1 g, 3 times / d, oral; 2 months after the number of patients with seizures have been controlled, but there are still 2 or so seizures every month. In order to better control seizures, add topiramate, from 50 mg / d,