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目的 探讨格雷夫斯病患者行甲状腺动脉介入栓塞治疗对甲状旁腺功能的影响。方法 对格雷夫斯病患者行双侧甲状腺上动脉 (17例 )加一侧甲状腺下动脉 (5例 )及加双侧甲状腺下动脉 (2例 )介入栓塞治疗前及 1个月后 ,测定血清甲状旁腺素、钙、磷浓度及游离三碘甲状腺原氨酸、游离甲状腺素、促甲状腺素水平的变化。结果 介入栓塞治疗后血清甲状旁腺素、钙、磷及促甲状腺素与术前比较无明显变化 (P >0 .0 5 ) ,而血清游离三碘甲状腺原氨酸、游离甲状腺素较术前明显降低 (P <0 .0 1)。结论 甲状腺介入栓塞治疗格雷夫斯病对甲状旁腺功能无明显影响。
Objective To investigate the effect of thyroid artery interventional embolization on parathyroid function in Graves’ disease. Methods Graves’ s two-sided upper thyroid artery (17 cases) plus one side of the thyroid artery (5 cases) and bilateral thyroid artery (two cases) before embolization and 1 month after treatment, serum Parathyroid hormone, calcium, phosphorus concentration and free triiodothyronine, free thyroxine, thyroid stimulating hormone levels. Results Serum parathyroid hormone, calcium, phosphorus and thyroid-stimulating hormone had no significant difference compared with those before operation (P> 0.05), while serum free triiodothyronine and free thyroxine were significantly lower than preoperative Significantly lower (P <0.01). Conclusions Graves’ s disease with thyroid interventional embolization has no significant effect on parathyroid function.