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目的:探讨下呼吸道感染应用四种抗生素方案治疗的药学结果。方法:按照随机数字法将我院接诊的下呼吸道感染患者200例均分为四组,各50例,分别采取头孢曲松钠、头孢唑肟钠、阿奇霉素、左氧氟沙星治疗,作为头孢曲松钠组、头孢唑肟钠组、阿奇霉素组、左氧氟沙星组,对比四组治疗效果、不良反应、费用及药学结果(疗效-成本)。结果:组间临床总有效率、不良反应发生率比较无明显差异(P>0.05);头胞曲松钠组、左氧氟沙星组费用、费用/疗效比均要明显低于头孢唑肟钠组、阿奇霉素组(P<0.05)。结论:下呼吸道感染采取左氧氟沙星、头孢曲松钠治疗药学价值更佳,值得借鉴。
Objective: To investigate the pharmacological effects of four antibiotics in lower respiratory tract infection. Methods: According to the random number method, 200 cases of lower respiratory tract infection admitted to our hospital were divided into four groups (n = 50 each) and were treated with ceftriaxone sodium, ceftizoxime sodium, azithromycin and levofloxacin respectively. Group, ceftizoxime sodium group, azithromycin group and levofloxacin group. The curative effect, adverse reaction, cost and the results of the four groups were compared (curative effect - cost). Results: There was no significant difference in the total effective rate of clinical and adverse reactions between the two groups (P> 0.05). The cost, cost / effect ratio of ceftriaxone sodium group and levofloxacin group were significantly lower than those of ceftizoxime sodium group, azithromycin Group (P <0.05). Conclusion: Levofloxacin and ceftriaxone sodium in lower respiratory tract infection are of better value in pharmacy and worth learning from.