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中科院上海生命科学院营养科学所周斌研究组首次利用遗传谱系示踪技术揭示了冠状动脉的新起源——心内膜。研究人员利用转基因小鼠结合谱系示踪技术,对冠状动脉的起源和发育机制进行研究,发现心脏中的一部分冠状动脉是在出生后新生成的,而不是由胚胎期已经形成的血管扩增而来的。心室壁外侧的冠状动脉来源于胚胎发育早期生成的血管。位于室间隔中的冠状动脉是在胚胎发育中期形成的。而心室壁内侧的冠状动脉是在出生后新生成的。该研究重新定义了冠状动脉的生长
Chinese Academy of Sciences, Shanghai Institutes for Biological Sciences, Zhou Bin research group for the first time using genetic lineage tracing technology revealed a new source of coronary artery - the endocardium. Using transgenic mice combined with pedigree tracing technology, the researchers studied the origin and development of coronary arteries and found that some of the coronary arteries in the heart are newly born after birth rather than from the blood vessels that have formed during the embryonic period Come on. The coronary arteries outside the walls of the ventricle originate from blood vessels that are generated early in embryonic development. Coronary arteries located in the interventricular septum are formed during embryonic development. The coronary arteries inside the ventricular wall are newly born after birth. The study redefined coronary artery growth