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目的 探讨老年糖尿病性微血管病变与血浆脂蛋白、血栓素B2 (TXB2 )、 6 -酮 -前列腺素E12(6KF)的相关性及临床意义。方法 测定 10 1例老年 2型糖尿病患者血浆脂蛋白、TXB2 、 6KF的含量。结果 糖尿病组血糖、血脂、TXB2 、TXB2 / 6KF下高于对照组 (P <0 0 1) ,6KF值于各组间无显著性差异 (P >0 0 5 )。结论 2型糖尿病老年患者严重代谢紊乱与微血管病密切相关。
Objective To investigate the correlation between the level of plasma lipoprotein, thromboxane B2 (TXB2) and 6 - keto - prostaglandin E12 (6KF) in elderly diabetic microangiopathy and its clinical significance. Methods The levels of plasma lipoprotein, TXB2 and 6KF in 101 elderly patients with type 2 diabetes mellitus were measured. Results The levels of blood glucose, blood lipids, TXB2 and TXB2 / 6KF in diabetic group were significantly higher than those in control group (P <0.01). There was no significant difference in 6KF between the two groups (P> 0.05). Conclusion Severe metabolic disorders in elderly patients with type 2 diabetes are closely related to microvascular disease.