论文部分内容阅读
研究缺铁性贫血 (IDA)儿童胃泌素水平的变化 ;观察间断补铁治疗儿童IDA的疗效。方法 :49例 IDA患儿每周口服一次铁制剂 (元素铁 2 mg/kg) ,共 1 2周。在治疗前后测查 Hb、ZPP、SF及血清胃泌素。结果 :经补铁治疗 ,Hb、SF均极显著性升高 (P<0 .0 1 ) ,ZPP则明显下降 (P<0 .0 1 ) ;IDA患儿血清胃泌素水平明显升高 ,与对照组比较差异显著 ,治疗后恢复正常。结论 :1每周一次间断补铁治疗儿童 IDA效果显著。 2 IDA患儿胃泌素的异常分泌可能与缺铁所致的胃粘膜萎缩有关
To study the changes of gastrin levels in children with iron deficiency anemia (IDA) and to observe the efficacy of intermittent iron supplementation in children with IDA. Methods: Forty-nine patients with IDA were given oral iron (iron 2 mg / kg) once a week for 12 weeks. Hb, ZPP, SF and serum gastrin were measured before and after treatment. Results: After treatment with iron supplementation, the levels of Hb and SF were significantly increased (P <0.01) and ZPP was significantly decreased (P <0.01). Serum gastrin levels were significantly increased in children with IDA, Compared with the control group, the difference was significant and returned to normal after treatment. Conclusion: 1 Weekly intermittent iron treatment in children with IDA significant effect. Abnormal secretion of gastrin in children with IDA may be related to gastric mucosal atrophy caused by iron deficiency