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目的探讨2009-2014年天津市河西区预防接种不良反应监测系统报告的不良反应问题,为疫苗安全使用提供科学依据。方法采取描述流行病学得方法对河西区监测系统收集的AEFI病例分析。结果 2009-2014年河西区通过AEFI信息管理系统接报15种疫苗引起的AEFI病例208例,总报告接种剂次为778 172剂,AEFI发生率为26.73/10万,12个社区卫生服务中心均有AEFI病例发生。常见临床症状为发热、接种局部红肿及硬结。较为严重有两例,均为接种吸附无细胞百白破疫苗后,一例为血管性水肿、另一例为血小板过敏性紫癜。结论全区12个社区卫生服务中心均有AEFI病例发生,AEFI报告发生率很低,预防接种的安全性良好。AEFI监测是科学评价接种疫苗的利弊,及时处置AEFI,增加大众对预防接种信心的有效措施。
Objective To investigate the adverse reactions reported by the surveillance system for immunization against hepatitis B virus in Hexi District, Tianjin City from 2009 to 2014 and to provide a scientific basis for the safe use of the vaccine. Methods AEFI case analysis of Hexi District monitoring system was conducted using a descriptive epidemiological method. Results A total of 208 AEFI cases were reported from Hexi Corridor through AEFI in 2009-2014. A total of 778 172 doses of AEFI and 26.73 / 100000 AEFI were reported. All 12 community health service centers AEFI cases have occurred. Common clinical symptoms of fever, inoculation of local swelling and induration. More serious in two cases, both vaccination cell-free diphtheria Baitiao vaccine, one case of angioedema, the other case of platelet-allergic purpura. Conclusion All AEFI cases occurred in 12 community health service centers throughout the district. The incidence of AEFI was very low and the safety of vaccination was good. AEFI monitoring is a scientific assessment of the pros and cons of vaccination, timely disposal of AEFI, increase public confidence in vaccination effective measures.