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目的分析替加环素治疗肺炎的状况。方法检索PubMed、SCI、EMbase、中国知网、万方5个数据库,通过EndNote 7.0软件,用文献计量学方法,对纳入文献的年代、发表国家、研究内容等进行统计分析。结果共纳入文献139篇,主要集中于高剂量替加环素治疗社区获得性肺炎、医院获得性肺炎和呼吸机相关肺炎的动物实验,以及以替加环素为基础的联合用药方法治疗肺炎。结论替加环素治疗肺炎集中于替加环素的高剂量应用和联合用药。
Objective To analyze the status of tigecycline in the treatment of pneumonia. Methods Five databases of PubMed, SCI, EMbase, CNKI and Wanfang were searched. By means of EndNote 7.0 software and bibliometrics methods, statistical analysis was carried out on the years, published countries and research contents of the included literature. Results A total of 139 articles were included and mainly focused on animal experiments of high-dose tigecycline for community-acquired pneumonia, hospital-acquired pneumonia and ventilator-associated pneumonia, and tigecycline-based combination therapy for pneumonia. Conclusion Tigecycline in the treatment of pneumonia is focused on high-dose tigecycline and combination therapy.