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目的研究兔蛛网膜下腔与颈部淋巴系统是否交通。方法对10只新西兰大白兔分别行脑脊液颈淋巴回流及颈淋巴管X-线造影检查。结果脑脊液颈淋巴回流造影显示造影剂在注射后7 min到达筛板,20 min到达视神经远端,30 min后从鼻腔漏出,同时颈部淋巴管显影。颈淋巴管造影检查显示注射初期造影剂在枕大孔周围流动缓慢,经视神经近端缓慢流动至视交叉;继之鼻中隔、筛板、内耳道、上矢状窦附近淋巴管及颈浅淋巴管显影。结论蛛网膜下腔与颈部淋巴系统之间相交通,在一定压力下,颈部淋巴管内淋巴液可逆行流入颅内;这一现象的病理生理学意义尚待进一步研究。
Objective To study whether the subarachnoid and cervical lymphatic system traffic. Methods Ten New Zealand white rabbits were examined by cerebrospinal fluid cervical lymphatic drainage and cervical lymphatic radiography. Results Cerebrospinal fluid lymphadenectomy showed that the contrast agent reached the plate 7 min after injection and reached the distal end of the optic nerve 20 min after injection. It leaked from the nasal cavity 30 min later, and the lymphatic vessels of the neck developed. Cervical lymphangiography showed that the initial contrast agent flowed slowly around the occipital foramen and slowly flowed to the optic chiasm through the proximal optic nerve; followed by nasal septum, sieve plate, internal auditory canal, lymphatic vessels near the sagittal sinus and superficial cervical lymphatic vessels development. Conclusions The subarachnoid and cervical lymphatic system communicate with each other. Under certain pressure, the lymphatic fluid in the neck can flow back into the intracranial. The pathophysiological significance of this phenomenon remains to be further studied.