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糖尿病神经病变是糖尿病最常见的慢性并发症之一。本文探讨血栓素A_2(TXA_2)、前列环素(PGI_2)、过氧化脂质(LPO)与糖尿病神经病变的关系。对象和方法研究对象分三组:1.正常人(NS)组35例(男17例、女18例),年龄38.3±13.6岁。2.糖尿病无神经病变(DN~-)组40例(男10例、女30例),年龄53.6±9.8岁,糖尿病病程5.2±5.6年。3.糖尿病神经病变(DN~+)组60例(男17例、女43例),年龄56.8±10.2岁,糖尿病病程6.3±4.2年。测定方法:均于清晨空腹取血。用放射免疫法测定血浆TXA_2和
Diabetic neuropathy is one of the most common chronic complications of diabetes. This article discusses the relationship between TXA_2, PGI_2, LPO and diabetic neuropathy. Subjects and methods The subjects were divided into three groups: 1. Normal (NS) group of 35 patients (17 males and 18 females), aged 38.3 ± 13.6 years. Diabetic patients with neuropathy (DN ~ -) group of 40 patients (10 males and 30 females), aged 53.6 ± 9.8 years, duration of diabetes 5.2 ± 5.6 years. Diabetic neuropathy (DN ~ +) group of 60 patients (17 males and 43 females), aged 56.8 ± 10.2 years, duration of diabetes 6.3 ± 4.2 years. Determination: Both in the morning fasting blood. Radioimmunoassay for plasma TXA_2 and