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目的:探讨丝裂霉素术中湿敷后联合角膜缘干细胞治疗复发性翼状胬肉的临床疗效。方法:36例复发性翼状胬肉37只眼,在显微镜下切除翼状胬肉,将含有0.2 mg/ml的丝裂霉素C的湿棉片敷在原胬肉生长的巩膜创面上,覆盖结膜组织,留置3~5 min后用生理盐水反复冲洗后行角膜缘干细胞移植术。结果:术后随访0.5~3 a,翼状胬肉复发2例。结论:丝裂霉素C联合角膜干细胞移植治疗复发性翼状胬肉,明显减少复发,安全有效,值得在临床上推广应用。
Objective: To investigate the clinical efficacy of mitomycin C intraoperative wet compress combined with limbal stem cells in the treatment of recurrent pterygium. Methods: Thirty-six patients with recurrent pterygium were enrolled. 37 cases of pterygium were removed under the microscope. A wet cotton pad containing 0.2 mg / ml mitomycin C was applied to the scleral wound surface of the original pterygium to cover the conjunctiva tissue , After 3 to 5 min indwelling rinse with saline repeated limbal stem cell transplantation. Results: All cases were followed up for 0.5 to 3 years and 2 cases had recurrence of pterygium. Conclusion: Mitomycin C combined with corneal stem cell transplantation in the treatment of recurrent pterygium, significantly reduce the recurrence, safe and effective, it is worth in the clinical application.