Synthesis and Crystal Structure of 5,7-Dimethoxy-2-phenylquinolin-4-yl Phenyloxy (N-L-Alanine ethyl

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5,7-Dimethoxy-2-phenylquinolin-4-yl phenyloxy (N-L-alanine ethyl ester) phosphoramidate (C28H29N2O7P, Mr = 536.17) has been synthesized by a facial phosphorylated reaction, and its structure was determined by IR, NMR, HR MS and X-ray single-crystal diffraction. The crystal belongs to triclinic, space group P1, with a = 11.375(2), b = 11.591(2), c = 11.638(2) , α = 109.46(3), β = 104.58(3), γ = 100.48(3)°, V = 1339.6(5) 3, Z = 2, Dc = 1.330 g/cm3, μ = 0.152 mm-1, F(000) = 564, the final R = 0.0654 and wR = 0.1546. In the crystal structure, the title compound is constructed by a centrosymmetric dimmer unit composed of a pair of π-π stacking diastereoisomers. The compound has a noteworthy feature in the framework, and such units are linked by two equal intermolecular P=O···H-N hydrogen bonds. 5,7-Dimethoxy-2-phenylquinolin-4-yl phenyloxy (NL-alanine ethyl ester) phosphoramidate (C28H29N2O7P, Mr = 536.17) has been synthesized by a facial phosphorylated reaction, and its structure was determined by IR, NMR, HR MS The crystal belongs to triclinic, space group P1 with a = 11.375 (2), b = 11.591 (2), c = 11.638 = 104.58 (3), γ = 100.48 (3) °, V = 1339.6 (5) 3, Z = 2, Dc = 1.330 g / cm3, μ = 0.152 mm- R = 0.0654 and wR = 0.1546. In the crystal structure, the title compound is constructed by a centrosymmetric dimmer unit composed of a pair of π-π stacking diastereoisomers. The compound has a noteworthy feature in the framework, and such units are linked by two equal intermolecular P = O ··· HN hydrogen bonds.
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