不稳定性心绞痛患者接受最适宜的内科治疗(包括卧床休息,吸氧,应用硝酸盐、钙拮抗剂和β-阻滞剂等)仍不能控制时,称为难治性心绞痛或顽固性心绞痛,主要见于多支冠状动脉阻塞性病变的基础上发生主动脉硬化斑块破裂、血栓形成者;其次是心脏合并症、心外因素所致。常见的心脏合并症有心功能不全、严重高血压、心脏瓣瓣病变(如风心病或老年瓣膜退行性变合并主动脉瓣关闭不 Unstable angina or refractory angina is the mainstay of unstable angina patients receiving optimal medical treatment (including bed rest, oxygen inhalation, nitrates, calcium antagonists and beta-blockers, etc.) Found in multiple coronary occlusive disease based on the occurrence of atherosclerotic plaque rupture, thrombosis were; followed by cardiac complications, caused by extracardiac factors. Common cardiac complications are heart failure, severe hypertension, heart valve disease (such as rheumatic heart disease or elderly degenerative valve degeneration and aortic valve closure is not