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目的观察舒芬太尼用于全子宫切除术后硬膜外自控镇痛的临床效果。方法 80例腰硬联合麻醉下行择期全子宫切除术患者,随机分为观察组和对照组,各40例。对照组采取舒芬太尼静脉自控镇痛,观察组采用舒芬太尼硬膜外自控镇痛。对比两组患者的临床疗效。结果休息时,两组患者的视觉模拟评分法(VAS)评分对比,差异均无统计学意义(P>0.05);咳嗽时,观察组患者8、12、24 h VAS评分低于对照组,差异均具有统计学意义(P<0.05)。观察组患者自控镇痛按压次数(16.3±10.4)次与舒芬太尼用药量(81.6±12.7)μg均少于对照组[(27.5±18.4)次、(172.5±24.6)μg],差异均具有统计学意义(P<0.05)。观察组患者不良反应发生率为35.00%,对照组为40.00%,对比差异无统计学意义(P>0.05)。结论舒芬太尼静脉自控镇痛和舒芬太尼硬膜外自控镇痛在临床中均有着较好的效果,但硬膜外自控镇痛的效果更加明显,值得在临床推广应用。
Objective To observe the clinical effect of sufentanil for postoperative epidural analgesia after total hysterectomy. Methods Eighty patients with elective hysterectomy underwent combined spinal and epidural anesthesia were randomly divided into observation group and control group, 40 cases in each group. Control group sufentanil intravenous controlled analgesia, observation group sufentanil epidural controlled analgesia. Compare the clinical efficacy of two groups of patients. Results At rest, there was no significant difference in visual analog scale (VAS) scores between the two groups (P> 0.05). At cough, the VAS score of the observation group was lower than that of the control group at 8, 12 and 24 hours All were statistically significant (P <0.05). In the observation group, the number of times of controlled analgesia (16.3 ± 10.4) and sufentanil (81.6 ± 12.7) μg were less than those in the control group [(27.5 ± 18.4) and (172.5 ± 24.6) μg], respectively Statistically significant (P <0.05). The incidence of adverse reactions was 35.00% in the observation group and 40.00% in the control group, but the difference was not statistically significant (P> 0.05). Conclusion Sufentanil intravenous controlled analgesia and sufentanil epidural analgesia in clinical have a good effect, but the effect of epidural controlled analgesia is more obvious, it is worth in the clinical application.