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目的了解妊娠妇女TORCH感染现况,为预防新生儿出生缺陷干预提供参考依据。方法 2013年4-12月采用按比例多阶段分层整群随机抽样方法,抽取11 953例符合生育政策、计划在3个月内怀孕的妊娠妇女进行问卷调查,采集其静脉血,用ELISA法检测TORCH特异性抗体。结果 11 953例妊娠妇女中巨细胞感染率为0.38%、弓形体为0.59%、梅毒为0.89%;其中渝东南地区(6个区县)巨细胞感染率最高为1.19%、一圈地区(22个区县)弓形体感染率最高为0.94%、渝东北地区(11个区县)梅毒感染率最低为0.23%;梅毒感染率随年龄增加而升高,弓形体感染率随文化程度升高而升高,梅毒感染率随着文化程度升高而下降;不同职业妇女弓形体感染率不同,公职人员最高为1.06%、农民最低为0.37%;既往具有不良妊娠结局史的计划妊娠妇女巨细胞、弓形体、梅毒阳性率均高于对照组。结论重庆地区妊娠妇女弓形体、巨细胞感染率处于一般水平,梅毒感染率较高,不良妊娠结局与TORCH感染有关,进行TORCH检查对优生优育有重要意义。
Objective To understand the status of TORCH infection in pregnant women and provide a reference for preventing the birth defects of newborns. Methods From April to December in 2013, 11 953 pregnant women who were pregnant according to reproductive policy and planned to be pregnant within 3 months were surveyed and collected by proportional sampling and multi-stage stratified random sampling. Blood samples were collected by ELISA TORCH-specific antibodies were detected. Results The infection rate of cytomegalovirus in 11 953 pregnant women was 0.38%, Toxoplasma was 0.59% and syphilis was 0.89%. The highest infection rate of cytomegalovirus was 1.19% in southeastern part of Chongqing (6 districts and counties) Toxoplasma gondii infection rate was the highest in 0.94%, the lowest in northeastern Chongqing (11 districts) syphilis infection rate was 0.23%; syphilis infection rate increased with age, Toxoplasma infection rate increased with the education level The prevalence of syphilis decreased with the increase of educational level. The prevalence of toxoplasm was different in different occupational women, the highest rate was 1.06% for public officials and 0.37% for peasants. The pregnant women with previous history of adverse pregnancy had giant cells, Toxoplasma, syphilis positive rate were higher than the control group. Conclusion The prevalence of Toxoplasma gondii and cytomegalovirus infection in pregnant women in Chongqing is at a general level, and the infection rate of syphilis is high. The adverse pregnancy outcome is related to TORCH infection. TORCH examination is of great importance to prenatal and postnatal care.