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目的:观察乐脉颗粒与西药合用治疗冠心病心绞痛血瘀证的临床疗效。方法:将72例冠心病心绞痛患者随机分为2组。对照组给予常规西药治疗,治疗组在西药常规治疗的基础上加用乐脉颗粒,治疗4周后观察2组疗效。结果:临床疗效治疗组显效10例,有效22例,无效4例,总有效率88.9%;对照组显效7例,有效17例,无效12例,总有效率66.7%。2组间比较差异有显著性(P<0.05)。心电图疗效治疗组显效6例,有效15例,无效15例,总有效率为58.3%;对照组显效4例,有效12例,无效20例,总有效率为44.4%。2组比较差异无显著性(P>0.05)。2组治疗前后血浆黏度、高切还原黏度、低切还原黏度、纤维蛋白原均有下降(P<0.05),但治疗组比对照组改变更明显,组间比较差异有显著性(P<0.05)。结论:中西医结合治疗冠心病心绞痛的疗效优于单纯西药治疗。
Objective: To observe the clinical efficacy of “Lemai Granule” combined with western medicine in the treatment of angina pectoris and blood stasis syndrome. Methods: 72 patients with coronary heart disease angina were randomly divided into two groups. The control group was given conventional western medicine. The treatment group was treated with Lemai Granules on the basis of routine treatment of western medicine. The curative effect was observed after 4 weeks of treatment. Results: The clinical curative effect of the treatment group was markedly effective in 10 cases, effective in 22 cases, ineffective in 4 cases, the total effective rate was 88.9%; in the control group markedly effective in 7 cases, effective in 17 cases, ineffective in 12 cases, the total effective rate was 66.7%. The difference between the two groups was significant (P <0.05). In the electrocardiogram treatment group, 6 cases were markedly effective, 15 cases were effective, 15 cases were ineffective, and the total effective rate was 58.3%. In the control group, 4 cases were markedly effective, 12 cases were effective and 20 ineffective. The total effective rate was 44.4%. There was no significant difference between the two groups (P> 0.05). The plasma viscosity, high shear reduction viscosity, low cut reduction viscosity and fibrinogen of the two groups before and after treatment decreased significantly (P <0.05), but the changes in the treatment group were more obvious than those in the control group, with significant difference between the two groups (P <0.05 ). Conclusion: The curative effect of integrated traditional Chinese and western medicine on angina pectoris is better than western medicine.