论文部分内容阅读
将32例妊娠高血压综合征（PIH）患者随机分为PIH组（15例）和青心酮（DHAP）治疗组（17例）,同时取相应年龄未孕妇女(16例）及正常孕妇（15例)作为对照组。采用放射免疫技术测定各组外周血（母血）、脐静脉血（胎血）的心纳素（ANP)、环磷酸腺苷（cAMP）、环磷酸鸟苷（cGMP）水平。结果发现:正常孕妇血浆ANP及cAMP、cGMP水平较未孕者略有增高,但无统计学意义（P>0.05）;而 PIH患者母血ANP及cGMP较未孕或正常孕妇明显增高（P 0.05), while the levels of ANP and cGMP in pregnant women with PIH were significantly higher than those of non-pregnant or normal pregnant women (P < (P <0.01). The plasma levels of ANP and cGMP in PIH patients after DHAP treatment were significantly lower than those before treatment (P <0.05), while cCMP was significantly increased (P <0.01) <0.01). Compared with the normal pregnant women, the blood levels of ANP and cGMP in PIH group were significantly increased (P <0.05) and cAMP was significantly lower; while the ANP and cGMP of PIH patients treated with DHAP were significantly higher than those in untreated PIH (P <0.05), and close to the level of normal pregnant women, cAMP was significantly increased (P <0.01).