论文部分内容阅读
单纯促皮质素缺乏(ICD)是不完全性垂体前叶机能减退的一种形式。大多数病例的病因学仍不清楚,但在一些研究中认为是自身免疫性垂体炎。ICD的临床症状与那些完全性垂体前叶机能减退如席汉氏综合征相似。闭经常常见于ICD妇女,它的发生机理不清楚,因为患本病的病人其促性腺机能并未受损。本文报道2例该病患者,她们是在产后使用氢化可的松后恢复排卵。作者指出皮质醇的存在是人类正常生殖腺机能的生理需要。 本文报道的2例患者未查到其他内分泌异常。
Simple corticotropin deficiency (ICD) is a form of incomplete hypophysial hypofunction. The etiology of most cases remains unclear, but in some studies it is considered autoimmune hypophysitis. The clinical symptoms of ICD are similar to those of complete hypothyroidism such as Sheath’s syndrome. Closure often occurs in women with ICD and its mechanism of occurrence is unclear because the patient’s gonadal function is not impaired. This article reports 2 patients with the disease, they are in postpartum use of hydrocortisone to restore ovulation. The authors point out that the presence of cortisol is a physiological requirement for normal gonadal function in humans. Two cases reported in this paper did not find other endocrine abnormalities.