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探讨天津市工业区大气污染对儿童非特异性免疫功能的影响，为大气环境综合治理提供卫生学依据。方法：把天津市某工业区作为污染区与对照区进行了环境流行病学调查，调查对象为７～１２岁学龄儿童。结果：工业污染区中ＳＯ２、ＮＯｘ、ＴｓＰ、ＣＯ超标率分别达５５．５５％、３４．４５％、９３．７８％、３２．２５％；分别是对照区的４．５５倍、４．１５倍、１．３０倍、１．５３倍；污染区儿童非特异性免疫指标唾液溶菌酶活性、ＳＩｇＡ含量、鼻粘膜细菌总数及溶血性链球菌数目与对照区比均有非常显著性差异（Ｐ＜０．００１或Ｐ＜０．０１）和显著性差异（Ｐ＜０．０５）。结论：提示污染区大气污染已对儿童健康状况产生明显危害。
To investigate the impact of air pollution on non-specific immune function of children in Tianjin Industrial Park and to provide hygiene basis for the comprehensive management of air environment. Methods: An industrial zone in Tianjin was used as a polluted area and a control area for environmental epidemiological survey. The survey subjects were school-age children aged 7-12 years. Results: The over-standard rates of SO2, NOx, TsP and CO in industrial pollution areas were 55.55%, 34.45%, 93.78% and 32.25% respectively, 4.55 times and 4.15 times respectively Times, 1.30-fold and 1.53-fold respectively. The salivary lysozyme activity, SIgA content, the total number of nasal mucosa and the number of hemolytic streptococcus in non-specific immune indicators of children in the contaminated area were significantly different from those in the control area (P < 0.001 or P <0.01) and significant difference (P <0.05). Conclusion: It is suggested that the air pollution in the polluted area has obvious harm to children’s health.