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目的探讨微波、聚焦超声法和高频电波环切术(LEEP刀)治疗宫颈糜烂的临床效果。方法选择武汉市中心医院宫颈糜烂患者320例,其中轻度80例,随机分配到微波组(微波治疗)和聚焦超声法组(聚焦超声法治疗),每组各40例;中度和重度糜烂各120例,随机分配到微波组、聚焦超声法组和LEEP组(LEEP刀治疗),每组中度或者重度糜烂各40例。评定三组患者治疗后1个月、治疗后2个月和治疗后3个月治愈、好转和无效情况。结果①聚焦超声法治疗后与微波治疗后,各时间段及各种程度的治愈率比较,差异无统计学意义(P<0.05)。②三种治疗方法对中度糜烂的治愈率比较,差异无统计学意义(P>0.05)。对于重度糜烂LEEP治疗的治愈率高于聚焦超声法和微波治疗(P<0.05),而聚焦超声法治疗和微波治疗比较差异无统计学意义(P>0.05)。结论微波和聚焦超声法治疗重度糜烂的疗效较差,LEEP治疗中、重度宫颈糜烂较前二者的治愈率高、愈合时间短,故轻度、中度糜烂可首选微波和聚焦超声法治疗,重度糜烂首选LEEP刀治疗。
Objective To investigate the clinical effects of microwave, focused ultrasound and high frequency electrosurgery (LEEP) on cervical erosion. Methods 320 patients with cervical erosion in Central Hospital of Wuhan were selected, of which 80 cases were mildly divided into microwave group (microwave treatment) and focused ultrasound group (focused ultrasound treatment group), 40 cases in each group. Moderate and severe erosion Each 120 patients were randomly assigned to microwave group, focused ultrasound group and LEEP group (LEEP knife treatment), each group of 40 cases of moderate or severe erosion. Three groups of patients were assessed 1 month after treatment, 2 months after treatment and 3 months after treatment, improvement and ineffectiveness. Results ① There was no significant difference in the cure rate after focused ultrasound and microwave treatment between different time points and various degrees (P <0.05). ② The cure rate of three kinds of treatment on moderate erosions, the difference was not statistically significant (P> 0.05). The cure rate of LEEP for severe erosion was higher than that of focused ultrasound and microwave (P <0.05), while there was no significant difference between focal ultrasound and microwave treatment (P> 0.05). Conclusion Microwave and focused ultrasound treatment of severe erosion is poor efficacy, LEEP treatment, severe cervical erosion than the former two high cure rate, healing time is short, so mild to moderate erosion can be preferred microwave and focused ultrasound treatment, Severe erosion preferred LEEP knife treatment.