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单纯性未分化畸胎瘤是最常见的第三种生殖细胞肿瘤,细胞遗传学研究结果表明组织学上的恶性度与肿瘤进展有关。通常,0—2期肿瘤为正常核型[46,ⅩⅩ],相对地说,预后良好,而恶性度高的肿瘤表现异常核型,预后不良。作者对1例3期卵巢畸胎瘤女患者的染色体进行研究,发现一个47,ⅩⅩ,+3核型。卵巢室管膜瘤是一种类似中枢神经系统分化肿瘤的卵巢肿瘤,尽管其表现与卵巢瘤相似,但可通过对神经胶质原纤维酸性蛋白进行免疫组织化学染色阳性而鉴别。作者报告一例38岁,患卵巢类室管膜瘤的妇女,核型为56,ⅩⅩ,
Simple undifferentiated teratoma is the most common third germ cell tumor, cytogenetic studies have shown that histological malignancy and tumor progression. Normally, tumors of stage 0-2 are of a normal karyotype [46, XX], with relatively good prognosis, whereas malignant tumors show aberrant karyotype with poor prognosis. The authors studied the chromosomes of a female patient with stage 3 ovarian teratoma and found a 47, XX, +3 karyotype. Ovarian ependymoma is a type of ovarian tumor resembling a central nervous system differentiated tumor that, despite being similar in appearance to ovarian tumors, can be identified by immunohistochemical staining of glial fibrillary acidic protein. The authors report a 38-year-old woman with ovarian ependymoma with Karyotype 56, XX,