严重糖尿病酮症酸中毒时应用胰岛索的速度和途径殊为重要。静注胰岛素,因其血浆半衰期仅4～5分钟,需频频重复注射。皮下注射胰岛索,吸收缓慢,故其开始作用时间延迟。肌注胰岛素,半衰期约2小时,作用时间介于静注与皮下注射之间;既使开始作用时间不太延缓,又可适当延长作用时间。作者因此采用小剂量肌注胰岛素治疗糖尿病昏迷患者。所观察的17例均系未控制的严重糖尿病。其中14 Severe diabetic ketoacidosis, the application of islet speed and pathways are important. Insulin intravenous injection, because of its plasma half-life of only 4 to 5 minutes, frequent repeated injection. Subcutaneous injection of pancreatic islets, absorption is slow, so the onset of time delay. Insulin intramuscular injection, half-life of about 2 hours, the role of time between intravenous injection and subcutaneous injection; even if the onset of action is not too slow, but also appropriate to extend the duration of action. The authors therefore used low-dose intramuscular insulin in patients with diabetic coma. The observed 17 cases were all uncontrolled severe diabetes. Of which 14