病例报告先证者(Ⅱ_4),女,53岁,间歇性右上腹痛十余年,加重两周入院。查体:体温、脉搏、血压均在正常范围,全身皮肤及巩膜轻度黄染,浅表淋巴结未扪及。心肺检查(-),右上腹有局限性压痛,莫非氏征(+),肝脾未扪及,肝区叩痛(+)。实验室检查:血色素100g/L,白细胞22×10~9/L,中性 Case report proband (Ⅱ_4), female, 53 years old, intermittent right upper quadrant pain more than ten years, increased two weeks admission. Physical examination: body temperature, pulse, blood pressure are in the normal range, the body skin and scleral mild yellow dye, superficial lymph nodes not palpable. Cardiopulmonary examination (-), right upper quadrant tenderness limitations, Moxi’s sign (+), liver and spleen not palpable, liver percussion (+). Laboratory tests: hemoglobin 100g / L, white blood cells 22 × 10 ~ 9 / L, neutral