既往的在体实验表明,在温和的无害刺激下,胃粘膜细胞将产生“适应性细胞保护作用”,能对随后给予的强烈刺激产生抵抗作用,其作用机制可能与血管、神经和激素等有关。最近,日本Keiya Nakamura等提出,适应性细胞保护作用是机体的一种自我保存机制,与上述因素无关。他们把离体原代培养的豚鼠胃粘膜细胞分为两组,实验组细胞置于43℃环境中,对照组细胞置于37℃环境中,然后观察两组细胞 Previous in vivo experiments showed that gastric mucosal cells will produce “adaptive cytoprotective effect” under mild and harmless stimulation and may have a resistance to the strong stimulation subsequently given, and its mechanism may be related to blood vessels, nerves and hormones related. Recently, Keiya Nakamura et al proposed that adaptive cytoprotection is a self-preservation mechanism of the body and has nothing to do with the above factors. They divided the primary cultured guinea pig gastric mucosal cells into two groups, the experimental group cells were placed in the environment of 43 ℃, the control group cells were placed in a 37 ℃ environment, and then observed two groups of cells