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班氏吴策线虫引起人类淋巴丝虫病。该病全球分布,估计感染人群达八千二百万,并引起象皮肿、鞘膜积液和淋巴结炎等临床症状。防治该病的过程中由于缺乏安全有效的一次性治疗药剂而受到限制。当海群生总剂量≥72mg/kg时才能有效地对抗丝虫成虫,而人一次只能耐受6mg/kg,所以需多次给药。单剂的伊维菌素能出奇地降低微丝蚴的密度,被认为是丝虫病群体防治的潜在的药物。但是单剂量伊维菌素的长期效果仍不及
Banczoechia cinctus causes human lymphatic filariasis. The disease is globally distributed and an estimated 82 million people are infected and cause clinical symptoms such as elephantiasis, hydrocele and lymphadenitis. The prevention and treatment of the disease is limited by the lack of a safe and effective one-shot remedy. When the total population of sea life is ≥72mg / kg, it can effectively fight the filarial adults, while the human one can only tolerate 6mg / kg, so the need for multiple administration. A single dose of ivermectin surprisingly reduces the density of microfilaria, which is considered as a potential drug for the prevention and treatment of filariasis. However, the long-term efficacy of a single dose of ivermectin is still low