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目的 :探讨青年人胃癌生物学行为特点及诊疗措施。方法 :就其临床表现特征、病理组织学类型、外侵转移情况以及治疗、预防等加以分析。结果 :组织学以低分化腺癌和未分化癌居多 ,易出现转移、浸润。手术切除组 1、3、5年生存率明显高于未切除组。且 1年生存率两组差异有显著性 ( P<0 .0 5 )。3年、5年生存率因未切除组均为 0 ,故未作统计学处理。结论 :青年人胃癌组织分化程度差、恶性度高、侵袭力强、晚期病例多、预后差。早诊、早治及合理的围手术期综合治疗是提高生存率的关键。
Objective: To explore the characteristics of biological behavior and treatment measures in young patients with gastric cancer. Methods : To analyze the clinical manifestations, histopathological types, invasion and metastasis, and treatment and prevention. Results: Histologically, poorly differentiated adenocarcinomas and undifferentiated carcinomas were predominant, and metastasis and infiltration were easy to occur. The 1-, 3-, and 5-year survival rates in the surgical resection group were significantly higher than those in the unresectable group. The one-year survival rate was significantly different between the two groups (P<0.05). The 3-year and 5-year survival rates were 0 for the unresected group, so no statistical treatment was performed. Conclusion : Young patients with gastric cancer have poor differentiation, high degree of malignancy, strong invasiveness, more advanced cases, and poor prognosis. Early diagnosis, early treatment and reasonable perioperative comprehensive treatment are the keys to improving survival.